The first rodenticides were short-acting anticoagulants like warfarin , which caused death from internal bleeding but rodents became resistance, so companies developed longer-acting, more toxic anticoagulants such as brodifacoum, bromadiolone, difenacoum and difethialone. These products are still available yet their use is restricted. Now even more effective rodenticides have been developed such as bromethalin, cholecalciferol and zinc phosphide. Bromethalin targets the central nervous system, causing tremors, loss of coordination, seizures, paralysis and death. Cholecalciferol is actually vitamin D3, which increases calcium levels in the blood and high levels cause heart problems, kidney failure and death. Zinc phosphide is converted in the body to highly toxic phosphine gas, which smells like rotten garlic or dead fish.
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